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Karyopharm Therapeutics, Inc. (NASDAQ: KPTI)

Securities Class Action

  • Date:
  • 10/4/2019
  • Company Name:
  • Karyopharm Therapeutics, Inc.
  • Stock Symbol:
  • KPTI
  • Status:
  • Investigating

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NEW YORK, October 4, 2019 – Bragar Eagel & Squire is investigating certain officers and directors of Karyopharm Therapeutics, Inc. (NASDAQ: KPTI) following a class action complaint that was filed against Karyopharm on July 23, 2019.

The Complaint alleges that during the Class Period, defendants falsely represented the safety and efficacy of selinexor, a pharmaceutical drug intended for the treatment of various types of cancer that Karyopharm was in the process of developing. Specifically, defendants’ material misrepresentations and omissions center on defendants’ claims regarding results from clinical trials for selinexor's treatment of patients with certain types of blood cancer. During the Class Period, defendants claimed that selinexor studies showed that selinexor was “well-tolerated” by patients and explained that there were “no new clinically significant adverse events in the patients receiving selinexor.” The company repeatedly touted the commercial prospects for selinexor and consistently described selinexor as having a "predictable and manageable tolerability profile" and a "very nice safety profile." In reality, selinexor was unsafe with limited efficacy. The truth was revealed on February 22, 2019, when the Federal Drug Administration ("FDA") released a briefing document that expressed serious concerns with selinexor. Specifically, the FDA revealed that, contrary to Karyopharm’s assurances, one of the previously cancelled selinexor trials had resulted in “worse overall survival” for certain patients treated with selinexor, which “highlight[ed] the toxicity of this drug.” The FDA unambiguously concluded that “[t]reatment with selinexor is associated with significant toxicity” and has “limited efficacy.”

If you are a long-term stockholder of Karyopharm securities, have information, would like to learn more about these claims, or have any questions concerning this announcement or your rights or interests with respect to these matters, please contact Melissa Fortunato by email at investigations@bespc.com, or telephone at (212) 355-4648, or by filling out the contact form below. There is no cost or obligation to you.
The individual or institution below (“Plaintiff”) has reviewed and agrees to the Bragar Eagel & Squire, P.C. (“BESPC”) retainer agreement and authorizes BESPC to prosecute an action on Plaintiff’s behalf under the federal securities laws or applicable state laws to recover damages on behalf of investors in Karyopharm Therapeutics. BESPC will prosecute the action on a full contingency basis and will forward all costs and expenses.
 

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